Quantity: 5 MG
Product name: β-Amyloid (1–42, R5G)
Synonyms: D A E F G H D S G Y E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V I A
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Beta-amyloid protein is thought to play a major role in the development of Alzheimer’s disease. The more common form of the peptide has only 40 amino acids, but the 42AA peptide has a greater tendency to form plaques.High levels of plasma Aβ42 in patients with acute intracerebral hemorrhage are associated with a poor functional prognosis. Amyloid fibrils have been shown to exert their toxicity by modulating the immune system. Amyloid fibrils formed from different pathological or non-pathological proteins or peptides activate macrophages and microglia, leading to the secretion of pro-inflammatory molecules, such as TNF-α, IL-6, IL-1β and NO.
Usage: For Scientific Research Use Only, Not for Human Use.