$ 330.0
Quantity: 50mg
In stock
Description
Product name: EIEKFDKSKLK
Catalog#: 2214008
CAS NO.:
Sequence: Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys
M.W: 1364.59
M.F.: C62H105N15O19
Purity: 95%
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: The human thymosin β4 fragment EIEKFDKSKLK showed antibacterial activity against staphylococcal strains and Pseudomonas aeruginosa ATCC 15442 at concentrations from 12.5 to 6.2 mg/ml and inhibited biofilm formation at sub-inhibitory concentrations (3.1-0.75 mg/ml). The activity of the fragment in inhibiting biofilm formation, could be due to the conformations highlighted by the MD simulations, suggesting its interaction with the bacterial membrane. Human thymosin β4 fragment can be considered a promising lead compound to develop novel synthetic or recombinant derivatives with improved pharmaceutical potential.
