Antibacterial & cell-penetrating peptides

Antimicrobial peptides (AMPs) represent a vast array of molecules produced by virtually all living organisms as natural barriers against infection. AMPs are in various stages of drug development, from early preclinical studies to phase III of clinical studies . Compounds with different molecular sizes were examined, from the peptide containing 24 amino acids, OP-145, to the modified tripeptide LTX-109 , both in phase II of clinical trial. Trojan peptides or cell-penetrating peptides (CPP) are natural or designed peptides identified as cellular membrane-crossing molecules, in particular through their potency to vehiculate various kinds of compounds to the cytoplasm and nucleus of living cells.

Showing 1–16 of 124 results