Ubiquicidin(29-41)

$ 550.0

Quantity: 50 MG

In stock

SKU: 1369003 Categories: ,

Description

Product name: Ubiquicidin(29-41)

Catalog#: 1369003

Organism: Human

Synonyms: 40S ribosomal protein S30,UBI 29-41,

CAS NO.:

Sequence: TGRAKRRMQYNRR

Modifications:

M.W:1692.96

M.F.:C68H121N31O18S1

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Ubiquicidin(29-41) is a cationic, synthetic antimicrobial peptide ubiquicidin fragment. Antimicrobial peptides such as ubiquicidin (UBI) are believed to differentiate between mammalian and bacterial or fungal cells. (99m)Tc-UBI29-41 was previously tested for detecting infection in humans using SPECT. For the present study, the UBI fragment UBI29-41 (TGRAKRRMQYNRR) was conjugated to 1,4,7-triazacyclononane-triacetic acid (NOTA), radiolabeled with (68)Ga, and investigated in a rabbit infection model. (68)Ga-NOTA-UBI29-41 was strongly localized in bacteria-infected areas and minimally detected in a sterile inflammation area in rabbit muscles. The findings propose this compound to be an excellent first-line PET/CT tracer to allow the distinguishing of infection from inflammation.

Uniprot ID: P62861

 

Usage: For Scientific Research Use Only, Not for Human Use.