FF

Description

Product name: FF

Catalog#: 1502026

Synonyms: Di-L-phenylalanine, (S)-2-((S)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid,

Sequence: Phe-Phe

Cas#: 2577-40-4

M.W: 312.37

M.F.: C18H20N2O3

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: One of the most studied short building blocks is the diphenylalanine peptide (L-Phe-L-Phe; FF), the core recognition motif of the Alzheimer’s β-amyloid peptide. A series of studies have shown that the peptide and its derivatives can self-assemble into highly ordered structures and other forms with nanoscale order, such as hydrogels. A unique property of the FF building block is its ability to form hollow tubular assemblies, most likely by the closure of two-dimensional surfaces. These assemblies can serve as casts for the fabrication of silver nanowires and have remarkable stiffness. The vibrational spectra and birefringence of nanotubes suggest that they may share some structural properties with amyloid fibrils. On the other hand, work by Görbitz has provided evidence that nanotubes may be structurally similar to three-dimensional FF crystals, which contain parallel helical channels with six peptides per helical turn and a diameter of 9.2 Å.

Compound ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.