P42

Description

Product name: P42

Catalog#: 1808166

Synonyms: hHtt(480–502),

CAS NO.:

Sequence: AASSGVSTPGSAGHDIITEQPRS

M.W:2224.07

M.F.:C91H149N29O36

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description:  Huntington’s Disease (HD) is a progressive neurodegenerative disorder caused by an abnormal expansion of polyQ (>35) domain in the N-terminus of the Huntingtin protein (Htt).A 23aa peptide (P42), lying in the N-terminus (position 480–502 aa) of normal human Htt (hHtt), able to prevent aggregation in cellulo in HeLa cells, and to retain protective properties on different phenotypes induced by the expression of the polyQ-Htt in vivo in a Drosophila model of HD (on eye degeneration, axonal trafficking and larval locomotion for instance).

Compound ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.