$ 800.0
Quantity: 50 MG
Available on backorder
Description
Product name: Tkip
Catalog#: 1809058
Synonyms: tyrosine kinase inhibitor peptide,
CAS NO.:
Sequence: WLVFFVIFYFFR
Modifications:
M.W:1682.90
M.F.:C93H118N16O14
Quantity: 5mg
Purity: 95% by HPLC
Counter ion: Trifluoroacetate
Format: Lyophilized powder
Description: Our laboratory recently designed a short 12-mer peptide, WLVFFVIFYFFR, which binds to the autophosphorylation site of JAK2, resulting in inhibition of its autophosphorylation as well as its phosphorylation of IFNGR subunit IFNGR-1. The JAK2 tyrosine kinase inhibitor peptide (Tkip) did not bind to or inhibit tyrosine phosphorylation of vascular endothelial growth factor receptor or phosphorylation of a substitute peptide by the protooncogene tyrosine kinase c-Src. Tkip, as with SOCS-1, also inhibited EGFR autophosphorylation.
UniProt ID:
Usage: For Scientific Research Use Only, Not for Human Use.
