2,3,5,4′-Tetrahydroxyl-diphenylethylene-2-O-beta-D-glucoside

Description

Product name: 2,3,5,4′-Tetrahydroxyl-diphenylethylene-2-O-beta-D-glucoside

Synonym：2,3,5,4′-Tetrahydroxytoluylene-2-beta-D-glucoside ; 2,3,5,4′-Tetrahydroxystilbene 2-O-glucosid

Catalog #: BP0039

Purity: 98%

CAS No.:82373-94-2

Molecular Formula: C₂₀H₂₂O₉

Molecular Weight: 406.387

Botanical Source:Crataegus spp. and other plant spp. Astringent black tea

Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Descriptions:
2,3,5,4′-Tetrahydroxyldiphenylethylene-2-O-glucoside(TSG) blocks the proliferation of PASMCs induced by PDGF-BB through arresting the cell cycle in G0 / G1 phase, indicates that TSG suppress PDGF-BB-induced PASMCs proliferation is associated with an inhibition of AKT / GSK3β signaling pathways.[1]
Stilbeneglycoside has protective effects of preconditioning in an ischemia/reperfusion model of HUVECs.[2]
Stilbene glycoside has active effect on proliferation and differentiation of rat’s osteoblasts, can promote the mature of osteoblasts.[3]

References:
[1] Guan W J, Xu C. J Med Res, 2015, 44 (06): 122-6.
[2]Li-ping, Zhang-ping, LIAO, et al. Acta Pharmacol Sin, 2010, 31(4):405-12.
[3] Jiwei W U. Hebei MedJ, 2014(05):654-6.
[4] Gang D , An S F, Liu CY. West China J Pharm Sci, 2003, 17(4):297-9.