$ 250.0

Quantity: 1000 MG

In stock

SKU: BP0092 Category:


Product name: 6-Gingerol

Synonym: 5-O-Methylvisamminol glucoside

Catalog #: BP0092

Purity: 98%

CAS No.: 23513-14-6

Molecular Formula: C17H26O4

Molecular Weight: 294.391

Botanical Source:ginger (Zingiber officinale)

Analysis Method: HPLC-DAD or/and HPLC-ELSD

Identification Method: Mass, NMR

The purity(assay) of  90%, 95% and 98% is available for food, nutrition and cosmetics request, except for R&D and reference standard.


1, Analgesic and anti-inflammatory activities of [6]-gingerol
Journal of Ethnopharmacology Volume 96, Issues 1–2, 4 January 2005, Pages 207–210
In the present study, the analgesic and anti-inflammatory effects of [6]-gingerol, which is the pungent constituent of ginger, were performed. Intraperitoneal administration of [6]-gingerol (25 mg/kg–50 mg/kg) produced an inhibition of acetic acid-induced writhing response and formalin-induced licking time in the late phase. [6]-Gingerol (50 mg/kg–100 mg/kg) also produced an inhibition of paw edema induced by carrageenin. These results suggested that [6]-gingerol possessed analgesic and anti-inflammatory activities.
2, [6]-Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo
    Biochemical and Biophysical Research Communications  Volume 335, Issue 2, 23 September 2005, Pages 300–308
3, Molecular targets of [6]-gingerol: Its potential roles in cancer chemoprevention.
   Biofactors. 2010 May-Jun;36(3):169-78. doi: 10.1002/biof.78.
A wide variety of phenolic compounds derived from spices possess potent antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic activities. [6]-gingerol (1-[4′-hydroxy-3′-methoxyphenyl]-5-hydroxy-3-decanone) is the major pungent principle of ginger, with numerous pharmacological properties including antioxidant, anti-inflammation, and antitumor promoting properties. It could decrease inducible nitric oxide synthase (iNOS) and tumor necrosis factor alpha (TNF-alpha) expression through suppression of I-kappaB alpha (IkappaBalpha) phosphorylation, nuclear factor kappa B (NF-kappaB) nuclear translocation. Other antiproliferative mechanisms of [6]-gingerol include the release of Cytochrome c, Caspases activation, and increase in apoptotic protease-activating factor-1 (Apaf-1) as mechanism of apoptosis induction. Taken together, the chemopreventive potentials of [6]-gingerol present a promising future alternative to therapeutic agents that are expensive, toxic, and might even be carcinogenic.