$ 650.0

Quantity: 500 MG

In stock

SKU: BP0098 Category:


Product name: 7-Epitaxol


Catalog #: BP0098

Purity: 98%

CAS No.: 105454-04-4

Molecular Formula: C47H51NO14

Molecular Weight: 853.918

Botanical Source: Taxus brevifolia (Taxaceae)

Analysis Method: HPLC-DAD or/and HPLC-ELSD

Identification Method: Mass, NMR

The purity(assay) of  90%, 95% and 98% is available for food, nutrition and cosmetics request, except for R&D and reference standard.


7-Epitaxol is the major derivative of taxol found in cells and taxol (paclitaxel) is a well-known natural-source cancer drug.



J Pharmacol Exp Ther. 1987 Aug;242(2):692-8.    

Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium.    

The hydrolysis products of taxol have been isolated by high-performance liquid chromatography and identified by nuclear magnetic resonance and mass spectroscopy. In contrast to taxol, the major hydrolysis product, baccatin III, has little cytotoxic activity and does not promote in vitro microtubule assembly.


In cell culture medium, the concentration of taxol decreases with time and 7-Epitaxol, which exhibits properties comparable to those of taxol both on cells and on in vitro microtubuli polymerization, is formed. Baccatin III is found in small quantities in the cell medium, although it is barely detectable within the cells. 


It is concluded that 7-Epitaxol is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.