$ 250.0

Quantity: 50 MG

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Product name: Ac-HAAHVVH-NH2

Catalog#: 1501039




Sequence: Ac-His-Ala- Ala-His-Val- Val-His-NH2

Modifications: N-terminal actylation, c-terminal amide,



Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Copper(II), nickel(II) and zinc(II) complexes of the peptides Ac-HVVH-NH2 and Ac-HAAHVVH-NH2 have been studied by potentiometric, UV-vis, CD, EPR and NMR spectroscopic measurements. Both tetra and heptapeptides can form relatively stable macrochelates with copper(II), nickel(II) and zinc(II) ions, in which the ligands are coordinated via the side-chain imidazole functions. Formation of the macrochelates slightly suppresses, but cannot prevent the copper(II) and nickel(II) ion promoted deprotonation and coordination of the amide functionalities. The overall stoichiometry of the major species is [MH(-3)L]- with a 4N (=N-,N-,N-,Nim) coordination mode. The binding of HAAHVVH to palladium(II) is exclusive below pH 8 and the mixed metal species of palladium(II) and copper(II) ions are formed only in slightly basic solutions.

Uniprot ID:


Usage: For Scientific Research Use Only, Not for Human Use.