APEKTx1

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$ 3,500.0

Quantity: 1 MG

In stock (can be backordered)

SKU: 1601035 Categories: ,

Description

Product name: APEKTx1

Catalog#: 1601035

Synonyms: Kunitz-type serine protease inhibitor APEKTx1,

Sequence: INSICLLPKK QGFCRARFPR FYYNSSTRRC EMFYYGGCGG NANNFNTLEE  CEKVCLGYGE AWKAP

Modifications: disulfide(1-6,2-4,3-5),

M.W:

M.F.:

Purity: 95% by HPLC

Format: Lyophilized powder

Description: Sea anemone venom is a known source of interesting bioactive compounds, including peptide toxins which are invaluable tools for studying structure and function of voltage-gated potassium channels. APEKTx1 is a novel peptide isolated from the sea anemone Anthopleura elegantissima, containing 63 amino acids cross-linked by 3 disulfide bridges. Sequence alignment reveals that APEKTx1 is a new member of the type 2 sea anemone peptides targeting voltage-gated potassium channels (K(V)s), which also include the kalicludines from Anemonia sulcata. Similar to the kalicludines, APEKTx1 shares structural homology with both the basic pancreatic trypsin inhibitor (BPTI), a very potent Kunitz-type protease inhibitor, and dendrotoxins which are powerful blockers of voltage-gated potassium channels.

Uniprot ID: P86862

 

Usage: For Scientific Research Use Only, Not for Human Use.