Blood-depressing substance I

$ 4,850.0

Quantity: 1 MG

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Description

Product name: Blood-depressing substance I

Catalog#: 1738001

Organism: Mediterranean snakelocks sea anemone

Synonyms: BDS-1, Antihypertensive protein BDS-1,

CAS NO.:

Sequence: AAPCFCSGKPGRGDLWILRGTCPGGYGYTSNCYKWPNICCYPH

Modifications: disulfide(1-5,2-4,3-6),

M.W:

M.F.:

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Blood-depressing substance I (BDS-I), a 43 amino-acid peptide from sea anemone venom, is used as a specific inhibitor of Kv3-family potassium channels. We found that BDS-I acts with even higher potency to modulate specific types of voltage-dependent sodium channels.The biggest effect of BDS-I in central neurons was to enhance resurgent current in Purkinje neurons, an effect reflected in enhancement of sodium current during the repolarization phase of Purkinje neuron action potentials

Uniprot ID: P11494

 

Usage: For Scientific Research Use Only, Not for Human Use.