$ 360.0

Quantity: 1Gram

In stock

SKU: 1808127 Category:


Product name: Bronchogen

Catalog#: 1808127

Sequence: Ala-Glu-Asp-Leu

M.W: 446.45

M.F.: C18H30N4O9

Purity: 95%

Format: White powder

Description: We verified expression of CXCL12 and Hoxa3 transcription factors of differentiation in cultures of human embryonic pancreatic and bronchial cells and CXCL12 and WEGC1 factors in a culture of human prostatic fibroblasts. Reduced expression of these differentiation markers was detected in late-passage (aging) cultures. The expression of differentiation factors CXCL12, Hoxa3, and WEGC1 was tissue-specifically stimulated by short peptides: pancragen (Lys-Glu-Asp-Trp) in pancreatic cells, bronchogen (Ala-Glu-Asp-Leu) in bronchial epithelial cells, and vesugen (Lys-Glu-Asp) in fibroblasts. The inducing effect of peptides on the expression of differentiation factors was more pronounced in aged cultures, which can serve as a mechanism of their geroprotective effect.


Usage: For Scientific Research Use Only, Not for Human Use.