Cecropin A

Description

Product name: Cecropin-A

Catalog#: 1319001

Organism: Cecropia moth

Synonyms: Cecropin-C, P9A Protein, KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK-amide,

CAS NO.: 80451-04-3

Sequence: Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Glu-Lys-Val-Gly-Gln-Asn-Ile-Arg-Asp-Gly-Ile-Ile-Lys-Ala-Gly-Pro-Ala-Val-Ala-Val-Val-Gly-Gln-Ala-Thr-Gln-Ile-Ala-Lys-NH2

Modifications: C-terminal amide,

M.W: 4003.85

M.F.: C184H313N53O46

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Cecropin A is a natural antimicrobial peptide that exhibits rapid, potent and long-lasting lytic activity against a broad spectrum of pathogens. Its 37-amino acid sequence contains seven Lys, one Arg, one Glu, and one Asp for a net charge of +7 at neutral pH. On binding to lipid bilayers, it adopts a helix-break-helix motif, with amphipathic helical segments formed by residues 5–21 and 24–37. At low surface concentrations, both helical segments lie parallel to the lipid bilayer.  Cecropin A induces content release from lipid vesicles. Both L- and D- optical isomers of Cecropin A show comparable ability to kill bacterial cells.

Uniprot ID: P01507

 

Usage: For Scientific Research Use Only, Not for Human Use.