Product name: Corazonin
Organism: Fruit fly
CAS NO.: 122984-73-0
Modifications: N-terminal Pyr,C-terminal amide,
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Corazonin (Crz) is an undecapeptide and is a member of the neurohormone family that is ubiquitously present in arthropods with the exception of beetles, an aphid, and a spider mite. Crz was initially purified from the corpora cardiaca of the cockroach Periplaneta americana with a functional ability to accelerate the heartbeat.Corazonin executes diverse functions in various insects. Besides its initial assignment as an accelerator of heartbeat in cockroaches, additional functions ranging from pigment migration in the eye of locusts, melanization of the locust cuticle to initiating the ecdysis, and clock functions in the moth Manduca sexta. In Drosophila corazonin is supposed to regulate various stress responses, metabolism, female fecundity, and probably the downstream principal clock neuron. It had been reported that injected corazonin reduced the spinning rate, cocoon size, and hemolymph ecdysteroid level in the silkworm, meanwhile prolonging the pupal period.
Uniprot ID: Q26377
Usage: For Scientific Research Use Only, Not for Human Use.