$ 450.0
Quantity: 50 MG
Available on backorder
Description
Product name: CREKA
Catalog#: 1809077
Synonyms:
CAS NO.:
Sequence: Cys-Arg-Glu-Lys-Ala
M.W: 605.71
M.F.: C23H43N9O8S
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: The tumor-homing peptide Cys-Arg-Glu-Lys-Ala (CREKA) is a short linear pentapeptide that recognizes clotted plasma proteins and selectively homes in on tumors. Interestingly, this tumor-homing peptide has attracted special attention as it homes in on tumors amplifying its own homing activity by stimulating platelet clot formation. The experimental results obtained indicate that CREKA-modified nanoparticles accumulate in tumor vessels, where they induce additional local clotting and thereby produce new binding sites for more nanoparticles in tumor tissues without causing clotting in normal tissues.
Compound ID:
Usage: For Scientific Research Use Only, Not for Human Use.
Reference:
Int J Nanomedicine. 2015; 10: 2229–2248.
Acta Biomater. 2014;10:2622–2629.
Blood. 2010;116:2847–2856.
Nanomedicine. 2009;5:73–82.
Proc Natl Acad Sci U S A. 2007;104:932–936.
