D-Pleurocidin

$ 600.0

Quantity: 1mg

In stock

Description

Product name: D-Pleurocidin

Catalog#: 1351005

Synonyms: D-Plc,

Sequence: Gly-D-Trp-Gly-D-Ser-D-Phe-D-Phe-D-Lys-D-Lys-D-Ala-D-Ala-D-His-D-Val-Gly-D-Lys-D-His-D-Val-Gly-D-Lys-D-Ala-D-Ala-D-Leu-D-Thr-D-His-D-Tyr-D-Leu-NH2

Modifications: C-terminal amide,

M.W: 2710.15

M.F.: C129H193N37O28

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: D-Ple was stable in the proteases degrading of L-Ple indicated that D-amino acid substitutions could make peptides resistant to a proteolysis and thus D-Ple could exert its antimicrobial activity unimpaired. Also, this suggested that D-Ple or relevant derivatives might be potential candidates for clinical use. D-Ple showed much lower hemolytic activity than L-Ple at the highest level, and, there was no hemolysis at other concentration levels.

 

Usage: For Scientific Research Use Only, Not for Human Use.