Product name: Dermaseptin-S4
Organism: Sauvage’s leaf frog
Synonyms: DS IV,Dermaseptin-4,DS, ALWMTLLKKVLKAAAKALNAVLVGANA,
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Dermaseptin S4 (DS4) is an antimicrobial peptide derived from amphibian skin, which displays a broad spectrum of activity against bacteria, yeast, filamentous fungi, and herpes simplex virus type 1. We show here that DS4 inhibits cell-free and cell-associated HIV-1 infection of P4-CCR5 indicator cells and human primary T lymphocytes. The peptide is effective against R5 and X4 primary isolates and laboratory-adapted strains of HIV-1. Its activity is directed against HIV-1 particles by disrupting the virion integrity.
Uniprot ID: P80280
Usage: For Scientific Research Use Only, Not for Human Use.