Product name: Dihexa
Synonyms: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide (dihexa),
CAS NO.: 1401708-83-5
Modifications: N-terminal Hexanoyl, C-terminal amide,
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: The results of the study described here indicated that N-terminal modifications, and to a lesser extent C-terminal modifications, could improve the metabolic stability of Nle1-AngIV–derived tri- and tetrapeptides while preserving procognitive and synaptogenic activities. Expanding on these data, additional modifications intended to increase hydrophobicity and decrease hydrogen bonding potential yielded N-hexanoic-Tyr-Ile-(6) aminohexanoic amide (dihexa), a potent cognitive-enhancing molecule that proved to be very stable, capable of inducing spinogenesis/synaptogenesis at picomolar concentrations, slowly cleared from the blood compartment, and sufficiently BBB-permeable.
Usage: For Scientific Research Use Only, Not for Human Use.
Notice : Only for research purpose, not for human and veterinary use . This product is not available for US.