EIEKFDKSKLK

$ 350.0

Quantity: 10 MG

In stock

Description

Product name: EIEKFDKSKLK

Catalog#: 2214008

CAS NO.:

Sequence: Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys

M.W: 1364.59

M.F.: C62H105N15O19

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: The human thymosin β4 fragment EIEKFDKSKLK showed antibacterial activity against staphylococcal strains and Pseudomonas aeruginosa ATCC 15442 at concentrations from 12.5 to 6.2 mg/ml and inhibited biofilm formation at sub-inhibitory concentrations (3.1-0.75 mg/ml). The activity of the fragment in inhibiting biofilm formation, could be due to the conformations highlighted by the MD simulations, suggesting its interaction with the bacterial membrane. Human thymosin β4 fragment can be considered a promising lead compound to develop novel synthetic or recombinant derivatives with improved pharmaceutical potential.

Uniprot ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.