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SKU: 1208007 Category:


Product name: Exendin-4

Catalog#: 1208007

Synonyms: GLP-1 receptor agonist,Exenatide, HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-amide,

CAS NO.: 141758-74-9

Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Modifications: C-terminal amide,

M.W: 4186.6

M.F.: C184H282N50O60S

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Exendin-4, a GLP-1 receptor agonist originally isolated from the saliva of H. suspectum or Gila monster, is a peptide that shares sequence and functional homology with GLP-1. Both peptides have been demonstrated to stimulate insulin secretion, inhibit glucagon secretion, promote satiety and slow gastric emptying. Exendin-4 (Ex-4), a long-acting agonist of glucagon-like peptide-1 receptor, is a novel anti-diabetic drug that prevents β-cells against various toxicities. GLP-1 receptor agonist Ex-4 improves glucose homeostasis, shows antiobesity activity, without causing harmful side effects like fatty liver.

Drug Bank ID: http://www.drugbank.ca/drugs/DB01276


Usage: For Scientific Research Use Only, Not for Human Use.