$ 380.0

Quantity: 10Gram

In stock


Product name: Fmoc-Leu-Ser(Psi(Me,Me)pro)-OH

Synonym: (4S)-3-(Fmoc-Leu)-2,2-dimethyl-oxazolidine-4-carboxylic acid,(S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucyl)-2,2-dimethyloxazolidine-4-carboxylic acid,

Catalog #: 8304012

Purity: 95%

CAS No.: 339531-50-9

Molecular Formula: C27H32N2O6

Molecular Weight: 480.56

Description: Incorporation of the well-known secondary structure disrupting pseudoprolines (PsiPro) produced the desired product with high yield and allowed for the synthesis of the full length peptide. PsiPro-containing peptides exhibit flexible random-coil conformations devoid of fibril forming propensity. The pseudoproline derivatives induce a cisoid amide bond in the linear peptide backbone which facilitates cyclization. After cyclization, the turn inducers can be readily removed to afford cyclic tetrapeptides containing serine or threonine residues.