$ 750.0
Quantity: 50 MG
Available on backorder
Description
Product name: GLYX 13
Catalog#: 1809064
Synonyms: TPPT-amide, GLYX-13 peptide, GLYX13,
CAS NO.: 117928-94-6
Sequence: Thr-Pro-Pro-Thr-NH2
M.W: C18H31N5O6
M.F.: 413.47
Purity: 95% by HPLC
Counter ion: Acetate
Format: Lyophilized powder
Description: GLYX-13, a tetrapeptide (TPPT-amide), was found to readily cross the blood-brain barrier and modulate the NMDA receptor in a glycine-like fashion when examined pharmacologically and electrophysiologically. When GLYX-13 was administered to rats at 0.5-1.0mg/kg i.v., a significant enhancement in learning was observed using a hippocampus-dependent trace eye blink conditioning paradigm. These data indicate that the Glyxins are a new class of NMDA receptor modulators that may have therapeutic potential. Based on the broad agonist range in vitro and the potent cognitive-enhancing properties in a valid in vivo model of learning, GLYX-13 is a new drug candidate with potential for the treatment of cognitive disorders.
Compound ID: 14539800
Usage: For Scientific Research Use Only, Not for Human Use.
