$ 750.0

Quantity: 50 MG

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SKU: 1809064 Categories: ,


Product name: GLYX 13

Catalog#: 1809064

Synonyms: TPPT-amide, GLYX-13 peptide, GLYX13,

CAS NO.: 117928-94-6

Sequence: Thr-Pro-Pro-Thr-NH2

M.W: C18H31N5O6

M.F.: 413.47

Purity: 95% by HPLC

Counter ion: Acetate

Format: Lyophilized powder

Description: GLYX-13, a tetrapeptide (TPPT-amide), was found to readily cross the blood-brain barrier and modulate the NMDA receptor in a glycine-like fashion when examined pharmacologically and electrophysiologically. When GLYX-13 was administered to rats at 0.5-1.0mg/kg i.v., a significant enhancement in learning was observed using a hippocampus-dependent trace eye blink conditioning paradigm. These data indicate that the Glyxins are a new class of NMDA receptor modulators that may have therapeutic potential. Based on the broad agonist range in vitro and the potent cognitive-enhancing properties in a valid in vivo model of learning, GLYX-13 is a new drug candidate with potential for the treatment of cognitive disorders.

Compound ID: 14539800


Usage: For Scientific Research Use Only, Not for Human Use.