HMBA Linker

$ 450.0

Quantity: 100Gram

In stock

SKU: 8511003 Category:


Product name: HMBA Linker

Synonym: HMB linker,p-hydroxymethyl-benzoic acid linker,

Catalog #: 8511003

Purity: 98%

CAS No.: 3006-96-0

Molecular Formula: C14H20O6

Molecular Weight: 284.31

Compound ID: 76360

Description: A base labile 4-hydroxymethylbenzoic acid (HMBA) linker,it was effectively removed at pH=10. The HMBA linker was demonstrated to be stable to the conditions required for native chemical ligation, subsequent transformations and final purification. The benzyl ester, which forms the HMBA linker with the first amino acid, is stable to piperidine, used for Fmoc group removal, making the linkage applicable for chemical elongation of a peptide sequence with Fmoc strategies.