Human Obestatin

Description

Product name: Obestatin

Catalog#: 1204003

Organism: Human

Synonyms: FNAPFDVGIKLSGVQYQQHSQAL-NH2,

CAS NO.: 1081110-72-6

Sequence: Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Val-Gln-Tyr-Gln-Gln-His-Ser-Gln-Ala-Leu-NH2

Modifications: C-terminal amide,

M.W: 2546.88

M.F.: C116H176N32O33

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Obestatin is a 23-amino-acid, amidated peptide hormone that is mainly produced in the gastrointestinal tract and is derived from the posttranslational cleavage of the same peptide precursor as ghrelin. Obestatin and ghrelin have been shown to be stored in the same secretory vesicles. Obestatin is released in a pulsatile fashion, and its diurnal pattern of release is similar to that of ghrelin and GH. It is a potential therapeutic agent for skeletal muscle injury and would benefit other myopathies related to muscle regeneration. The stimulatory effect of obestatin on ACTH was associated with an increase in pituitary CRF receptors. Obestatin also reduced the expression of pituitary somatostatin receptors (sst1/sst2), which could serve to modify its impact on hormone secretion.

Uniprot ID: Q9UBU3

Compound ID: 91826105

 

Usage: For Scientific Research Use Only, Not for Human Use.