Interleukin-8,human

Description

Product name: Interleukin-8,human

Catalog#: 5101002

Source: chemical synthesis

Synonyms: chemokine 8,Emoctakin,Granulocyte chemotactic Protein 1,GCP-1,Monocyte-derived neutrophil chemotactic factor,MDNCF,Monocyte-derived neutrophil-activating peptide,MONAP

Neutrophil-activating protein 1,NAP-1,Protein 3-10C,T-cell chemotactic factor,

CAS NO.:

Sequence: AVLP(Cit)SAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS

Modifications: Cit5,disulfide(1-3,2-4),

M.W:

M.F.:

Purity: 95% by HPLC

Format: Lyophilized powder

Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine associated with the promotion of neutrophil chemotaxis and degranulation. This chemokine activates multiple intracellular signaling pathways downstream of two cell-surface, G protein-coupled receptors (CXCR1 and CXCR2). Interleukin-8 (IL-8) has been shown to play an important role in tumor growth, angiogenesis, and metastasis, and has close relationship with oxidative stress.

Uniprot ID: P10145

 

Usage: For Scientific Research Use Only, Not for Human Use.

 

Reference:

Veterinary Immunology and Immunopathology, Volume 159, Issues 1–2, 15 May 2014, Pages 97-102.

Journal of Pediatric Surgery, Volume 49, Issue 3, March 2014, Pages 385-389.

Journal of Infection and Chemotherapy, Volume 19, Issue 5, 2013, Pages 825-832.

International Immunopharmacology, Volume 16, Issue 2, June 2013, Pages 261-267.