Islet amyloid polypeptide(hIAPP)

$ 350.0

Quantity: 10 MG

In stock

SKU: 1219001 Categories: ,

Description

Product name: Islet amyloid polypeptide(hIAPP)

Catalog#: 1219001

Organism: Human

Synonyms: Amylin,Diabetes-associated peptide,DAP, Insulinoma amyloid peptide,

CAS NO.:

Sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY

Modifications: disulfide(2-7),c-terminal amide,

M.W:3906.30

M.F.:C165H262N50O56S2

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: IAPP is a 37 a.a. residues peptide with a disulfide bridge and an amidated C-terminus. Under normal conditions, it acts as a hormone, i.e., as insulin antagonist, being cosecreted along with insulin by pancreatic b-cells in the form of proIAPP, which is then further processed to yield the mature IAPP.The islet amyloid polypeptide (IAPP) is the main cytotoxic component of amyloidogenic deposits found in 95% of patients suffering from type II diabetes mellitus (T2DM).

Uniprot ID: P10997

 

Usage: For Scientific Research Use Only, Not for Human Use.