Quantity: 10 MG
Product name: Islet amyloid polypeptide(hIAPP)
Synonyms: Amylin,Diabetes-associated peptide,DAP, Insulinoma amyloid peptide,
Modifications: disulfide(2-7),c-terminal amide,
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: IAPP is a 37 a.a. residues peptide with a disulfide bridge and an amidated C-terminus. Under normal conditions, it acts as a hormone, i.e., as insulin antagonist, being cosecreted along with insulin by pancreatic b-cells in the form of proIAPP, which is then further processed to yield the mature IAPP.The islet amyloid polypeptide (IAPP) is the main cytotoxic component of amyloidogenic deposits found in 95% of patients suffering from type II diabetes mellitus (T2DM).
Uniprot ID: P10997
Usage: For Scientific Research Use Only, Not for Human Use.