KAFAK

$450.00

Quantity: 50 MG

Available on backorder

SKU: 1810001 Categories: ,

Description

Product name: KAFAK

Catalog#: 1810001

Synonyms: KAFAKLAARLYRKALARQLGVAA,

CAS NO.:

Sequence: H-Lys-Ala-Phe-Ala-Lys-Leu-Ala-Ala-Arg-Leu-Tyr-Arg-Lys-Ala-Leu-Ala-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH

M.W: 2487.01

M.F.: C114H196N36O26

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Brugnano et al investigated an anti-inflammatory cell-penetrating peptide KAFAKLAARLYRKALARQLGVAA, (KAFAK), which inhibits MAPK-activated protein kinase 2 (MK2). MK2 controls the synthesis of many pro-inflammatory cytokines, including IL-1, TNF-α, and IL-6. The MK2 pathway is triggered in osteoarthritis and promotes release of enzymes that degrade cartilage.

Uniprot ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.

 

Reference:

Nanomedicine: Nanotechnology, Biology and Medicine. Volume 12, Issue 7, October 2016, Pages 2095-2100.

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