$ 360.0

Quantity: 100Gram

In stock

SKU: 8246005 Category:


Product name: Moc-Tle

Synonym: Methoxycarbonyl-L-tert-leucine, (S)-2-((Methoxycarbonyl)amino)-3,3-dimethylbutanoic acid, (S)-N-(METHOXYCARBONYL)-TERT-LEUCINE,

Catalog #: 8246005

Purity: 98% by HPLC

CAS No.: 162537-11-3

Molecular Formula: C8H15NO4

Molecular Weight: 189.21

Compound ID: 11263950

Description: L-tert-Leucine and its derivatives are used as synthetic building blocks for pharmaceutical active ingredients, chiral auxiliaries, and ligands.  Cyclic peptides with alternating d- and l-amino acid residues containing tert-leucine residues in every second position can form peptide nanotubes.Owing to its bulky, inflexible and hydrophobic tert-butyl side chain, tert-leucine (Tle) finds increased use in templates or catalysts in asymmetric synthesis as well as in peptidic medicinal compounds. (S)-Tle, available through a large-scale enzymatic reductive amination process, has been incorporated into a variety of anti-AIDS and -cancer compounds. With two new routes to (R)-Tle coming available, the number of applications of both (R)- and (S)-Tle can be expected to increase considerably.

API: Boceprevir, Telaprevir