Neurokinin A

$ 270.0


In stock

SKU: 1211101 Category:


Product name: Neurokinin A

Catalog#: 1211101

Organism: Human

Synonyms: NKA,Neuromedin L,Substance K, Protachykinin-1, HKTDSFVGLM-amide,


Sequence: His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

Modifications: C-terminal amide,

M.W: 1133,3

M.F.: C50H80N14O14S

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: The classical tachykinins, substance P, neurokinin A and neurokinin B are predominantly found in the nervous system where they act as neurotransmitters and neuromodulators. Significantly reduced levels of these peptides were observed in neurodegenerative diseases. Neurokinin A proved to be an extremely potent inhibitor of drinking elicited by subcutaneous administration of hypertonic NaCl, and produced also a statistically-significant inhibition of food-associated drinking.  Recent European investigations have shown that persistently elevated (>50 pg/mL) plasma neurokinin A levels are associated with poor short-term survival in patients with midgut neuroendocrine neoplasms.

Uniprot ID: P20366


Usage: For Scientific Research Use Only, Not for Human Use.