Octreotide

$480.00

Quantity: 1Gram

10 in stock

SKU: 1225003 Category:

Description

Product name: Octreotide

Catalog#: 1225003

Synonyms: Growth hormone release-inhibiting factor,

CAS NO.: 83150-76-9

Sequence: D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol

Modifications: disulfide(2-7)

M.W: 1019.25

M.F.: C49H66N10O10S2

Purity: 95%

Counter ion: Acetate

Format: Lyophilized powder

Description: Octreotide is a synthetic peptide analog of somatostatin with the same pharmacologic effects. Its primary advantages over somatostatin are a longer half-life in the circulation, a higher potency, and good bioavailability after subcutaneous administration. The half-life of somatostatin is 2–3 minutes compared with 1–2 h for octreotide. Consequently, octreotide has largely supplanted somatostatin as a therapeutic agent for several diseases. The effects of somatostatin and octreotide occur as a result of binding to G protein receptors found throughout the body, including the gastrointestinal tract, pancreas, and the central nervous system. Octreotide decreases the production of gastrointestinal peptides, such as gastrin, secretin, gastric inhibitory peptide, cholecystokinin, neurotensin, motilin, and pancreatic polypeptide. This reduction in gastrointestinal peptides leads to multiple pharmacologic alterations in intestinal function.

 

Usage: For Scientific Research Use Only, Not for Human Use.

 

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