Product name: Octreotide
Synonyms: Growth hormone release-inhibiting factor,
CAS NO.: 83150-76-9
Counter ion: Acetate
Format: Lyophilized powder
Description: Octreotide is a synthetic peptide analog of somatostatin with the same pharmacologic effects. Its primary advantages over somatostatin are a longer half-life in the circulation, a higher potency, and good bioavailability after subcutaneous administration. The half-life of somatostatin is 2–3 minutes compared with 1–2 h for octreotide. Consequently, octreotide has largely supplanted somatostatin as a therapeutic agent for several diseases. The effects of somatostatin and octreotide occur as a result of binding to G protein receptors found throughout the body, including the gastrointestinal tract, pancreas, and the central nervous system. Octreotide decreases the production of gastrointestinal peptides, such as gastrin, secretin, gastric inhibitory peptide, cholecystokinin, neurotensin, motilin, and pancreatic polypeptide. This reduction in gastrointestinal peptides leads to multiple pharmacologic alterations in intestinal function.
Usage: For Scientific Research Use Only, Not for Human Use.