$ 700.0
Quantity: 50 MG
Available on backorder
Description
Product name: Peptide G16
Catalog#: 1809052
Synonyms:
CAS NO.:
Sequence: PRRYTIAALLSPYSWS
Modifications:
M.W:1879.99
M.F.:C88H133N23O23
Purity: 95% by HPLC
Counter ion: Trifluoroacetate
Format: Lyophilized powder
Description: Transthyretin, a plasma transport protein that is also relatively abundant in cerebrospinal fluid, has been shown to bind to Aβ, inhibit aggregation, and reduce its toxicity. Previously, we identified strand G of transthyretin as a specific Aβ binding domain. In this work we further explore and define the necessary features of this binding domain. We demonstrate that peptides derived from transthyretin bind Aβ and inhibit its toxicity. We also show that, although both transthyretin and transthyretin-derived peptides bind Aβ and inhibit toxicity, they differ significantly in their effect on Aβ aggregation.
UniProt ID:
Usage: For Scientific Research Use Only, Not for Human Use.
