$ 700.0
Quantity: 50 MG
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Description
Product name: pJAK2(1001–1013)
Catalog#: 1809054
Synonyms:
CAS NO.:
Sequence: LPQDKEYYKVKEP
Modifications:
M.W:1635.85
M.F.:C76H117N17O23
Purity: 95% by HPLC
Counter ion: Trifluoroacetate
Format: Lyophilized powder
Description: We focused on the activation loop of JAK2 to first develop inhibitors of its enzymatic activity independent of the physiological regulation of JAKs by SOCS. The autophosphorylation or activation loop region of human JAK2 became a focal point in our development of SOCS1 mimetics. The amino acid sequence of this region is 1001LPQDKEYYKVKEP for human JAK2 and is depicted symbolically as pJAK2(1001–1013) with the p of pJAK2 indicative of phosphorylation of tyrosine 1007, reflecting its activation state.
UniProt ID:
Usage: For Scientific Research Use Only, Not for Human Use.
