$ 750.0
Quantity: 50 MG
In stock
Description
Product name: Pseudin-2
Catalog#: 1355001
Organism: Paradoxical frog
Synonyms: Pen-4d,
CAS NO.:
Sequence: GLNALKKVFQGIHEAIKLINNHVQ
Modifications:
M.W:2685.14
M.F.:C122H202N36O32
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Pseudin-2, an AMP isolated from the skin of the South American paradoxical frog Pseudis paradoxa.We found that pseudin-2 organized to an aggregated state in aqueous solution, but that it dissociated into monomers upon binding to lipopolysaccharide (LPS), even though it did not neutralize LPS in Gram-negative bacteria. In addition, pseudin-2 assumed an α-helical structure in the presence of biological membranes and formed pores in both bacterial and fungal membranes, through which it entered the cytoplasm and tightly bound to RNA.
Uniprot ID: P83189
Usage: For Scientific Research Use Only, Not for Human Use.