$ 600.0
Quantity: 50mg
Description
Product name: Q90L Obestatin
Catalog#: 1204004
Organism: Human
Synonyms: hObQ90L, FNAPFDVGIKLSGVLYQQHSQAL,
Sequence: Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Val-Leu-Tyr-Gln-Gln-His-Ser-Gln-Ala-Leu-NH2
Modifications: C-terminal amide,
M.W: 2532.85
M.F.: C117H178N30O33
Purity: 95%
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Q90L obestatin was slightly more efficient than native obestatin in inhibiting ghrelin-induced cFos activation within the hypothalamic arcuate nucleus and the nucleus tractus solitarius of the brainstem. After ghrelin injection, 26% of NPY neurons in the arcuate nucleus expressed cFos protein and this number was significantly reduced by co-administration of Q90L obestatin. Q90L was also more potent that native obestatin in reducing ghrelin-induced inhibition of γ-aminobutyric-acid synaptic transmission onto GHRH neurons.
Uniprot ID: Q9UBU3
Usage: For Scientific Research Use Only, Not for Human Use.