Product name: Q90L Obestatin
Synonyms: hObQ90L, FNAPFDVGIKLSGVLYQQHSQAL,
Modifications: C-terminal amide,
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Q90L obestatin was slightly more efficient than native obestatin in inhibiting ghrelin-induced cFos activation within the hypothalamic arcuate nucleus and the nucleus tractus solitarius of the brainstem. After ghrelin injection, 26% of NPY neurons in the arcuate nucleus expressed cFos protein and this number was significantly reduced by co-administration of Q90L obestatin. Q90L was also more potent that native obestatin in reducing ghrelin-induced inhibition of γ-aminobutyric-acid synaptic transmission onto GHRH neurons.
Uniprot ID: Q9UBU3
Usage: For Scientific Research Use Only, Not for Human Use.