Q90L Obestatin

$ 600.0

Quantity: 50mg

SKU: 1204004 Category:


Product name: Q90L Obestatin

Catalog#: 1204004

Organism: Human


Sequence: Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Val-Leu-Tyr-Gln-Gln-His-Ser-Gln-Ala-Leu-NH2

Modifications: C-terminal amide,

M.W: 2532.85

M.F.: C117H178N30O33

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Q90L obestatin was slightly more efficient than native obestatin in inhibiting ghrelin-induced cFos activation within the hypothalamic arcuate nucleus and the nucleus tractus solitarius of the brainstem. After ghrelin injection, 26% of NPY neurons in the arcuate nucleus expressed cFos protein and this number was significantly reduced by co-administration of Q90L obestatin. Q90L was also more potent that native obestatin in reducing ghrelin-induced inhibition of γ-aminobutyric-acid synaptic transmission onto GHRH neurons.

Uniprot ID: Q9UBU3


Usage: For Scientific Research Use Only, Not for Human Use.