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Quantity: 1 G

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SKU: 1801040 Categories: ,


Product name: Hexapeptide-10

Catalog#: 1801040

Synonyms: alpha 6-integrin binding peptide, Serilesine

CAS NO.: 146439-94-3

Sequence: Ser-Ile-Lys-Val-Ala-Val

M.W: 615.76

M.F.: C28H53N7O8

Purity: 95% by HPLC

Counter ion: Acetate

Format: Lyophilized powder

Description: This bioactive peptide SIKVAV, located at the carboxyterminal portion of the laminin alpha 1 chain is liberated during tumor invasion through basement membranes. SIKVAV is involved in malignant transformation, cell proliferation, angiogenesis, and protease activity in a number of cell types. Because of its biological significance, this peptide has been proposed as a therapeutic agent. In salivary gland neoplasms, we have demonstrated that SIKVAV regulates the morphology and protease activity of a cell line (CAC2) derived from human adenoid cystic carcinoma. Despite its biological relevance, the mechanisms regulating the bioactivity of SIKVAV are not fully understood.

Compound ID: 10145673


Usage: For Scientific Research Use Only, Not for Human Use.