Tetrapeptide SSSR

Description

Product name: Tetrapeptide SSSR

Catalog#: 1808264

Synonyms:

Sequence: Ser-Ser-Ser-Arg

Modifications:

CAS NO.:

M.W: 435,43

M.F.: C15H29N7O8

Purity: 95% by HPLC

Format: White powder

Description: A tetrapeptide (SSSR) derived from the C domain of IGF-1 was sufficient for the synergistic promotion with FGLM-amide both of corneal epithelial migration in vitro and of wound closure in vivo. The activity of the SSSR peptide was sequence specific and its potency was similar to that of IGF-1. It was devoid, however, of both the mitogenic action of IGF-1 and the ability of the full-length molecule to induce neovascularization. Clinical application of the SSSR peptide would be expected to be free of potentially deleterious side effects associated with treatment with full-length IGF-1. Local administration of SSSR and FGLM-amide is thus a potential new strategy for the treatment of persistent corneal epithelial defects associated with neurotrophic keratopathy.

Compound ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.