Product name: Tripeptides FFF
Synonyms: bitter tripeptides,Tri-L-phenylalanine,
CAS NO.: 2578-81-6
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: The FF and FFF systems are similar in that they both self-organize into networks and β-sheet conformations. On the other hand, the FFF aggregates are more stable and the FFF networks have a higher propensity and are somewhat more stable than the FF networks. In the β-sheets of the simulations, FF and FFF show a tendency for unaligned and aligned strands, respectively. These differences stem from the different sizes of the FF and FFF monomers, due to which FFF have twice as many internal hydrogen-bonding groups compared to FF and an additional side chain. It is difficult to link the differences observed in the small systems of the simulations to the geometrical properties of the much larger FF nanotubes and FFF nanoplates.We found that the bitter tasting tri-peptides are more potent in activating T2R1 than the di-peptides tested. Among the peptides examined, the bitter tri-peptide Phe-Phe-Phe (FFF), is the most potent in activating T2R1 with an EC50 value in the micromolar range.
Usage: For Scientific Research Use Only, Not for Human Use.