Vasoactive intestinal peptide(VIP)

Description

Product name: Vasoactive intestinal peptide(VIP)

Catalog#: 1220101

Organism: Human

Synonyms: Vasoactive intestinal polypeptide,VIP,HSDAVFTDNYTRLRKQMAVKKYLNSILN,

CAS NO.: 37221-79-7

Sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn

Modifications: C-terminal amide,

M.W: 3326.83

M.F.: C147H237N43O43S

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: The neuropeptide vasoactive intestinal peptide (VIP) is expressed at high levels in the neurons of the suprachiasmatic nucleus (SCN). In the central and peripheral nervous system, vasoactive intestinal peptide (VIP), a 28-amino acid neuropeptide, is released to support neuronal survival in both physiological and pathological condition. VIP can inhibit the neurodegeneration induced by the loss of neurons. The indirect protection effect is mainly mediated by glial cells through the production of neurotrophic factor(s) and inhibition of proinflammatory mediators. By remolding the structure and improving the transfer efficiency of VIP, its nerve protective function could be further improved. Its neuroprotective action and efficacy in inhibiting a broad range of inflammatory responses make VIP or related peptides becoming a novel therapeutic method to neurodegenerative disorders (NDDs).

Uniprot ID: P01282

 

Usage: For Scientific Research Use Only, Not for Human Use.