[Chx2]EM

Description

Product name: [Chx2]EM

Catalog#: 2230103

Synonyms:

CAS NO.:

Sequence: Tyr–Chx–Phe–Phe–NH2

Modifications: 1-aminocyclohexane-1-carboxlylic acid (Chx),

M.W:

M.F.:

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: [Chx2]EM2, an EM2 analogue substituting 1-aminocyclohexane-1-carboxlylic acid (Chx) for Pro. X-ray diffraction analysis revealed that [Chx2]EM2 is folded into the trans-form of Tyr–Chx. The manner of folding resembled that seen in D-TIPP, an EM analogue incorporating tetrahydroisoquinoline carboxylic acid, as well as the β-turn of Leu-enkephalin. Selectivity for the opioid μ-receptor was fairly well conserved by [Chx2]EM, suggesting that the folded form is important for μ-selectivity.

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Usage: For Scientific Research Use Only, Not for Human Use.