Epinecidin-1

Description

Product name: Epinecidin-1

Catalog#: 1367001

Organism: Hoplobatrachus rugulosus

Synonyms: GFIFHIIKGLFHAGKMIHGLV-amide,

Sequence: Gly-Phe-Ile-Phe-His-Ile-Ile-Lys-Gly-Leu-Phe-His-Ala-Gly-Lys-Met-Ile-His-Gly-Leu-Val-NH2

Modifications: C-terminal amide,

M.W: 2334.91

M.F.: C114H176N30O21S

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Epinecidin-1 is active against Gram-negative and -positive bacteria, viruses, Candida albicans, and Trichomonas vaginalis in vitro and in vivo. Morphological changes in bacteria treated with epinecidin-1 suggest that the peptide disrupts membranes and may thus prevent or delay the development of microbial resistance. In addition to its direct antibacterial effects, epinecidin-1 appears to regulate the host innate immune system in response to Vibrio vulnificus infection in zebrafish and also mediates cytokine secretion in response to bacterial infection in mice. Consequently, epinecidin-1, like other AMPs, possesses several important activities, including broad antibacterial, antiendotoxin, antitumor, antiviral, and immunomodulatory properties.

Uniprot ID: Q6JWQ9

 

Usage: For Scientific Research Use Only, Not for Human Use.