$ 450.0
Quantity: 100Gram
In stock
Description
Product name: HMBA Linker
Synonym: HMB linker,p-hydroxymethyl-benzoic acid linker,
Catalog #: 8511003
Purity: 98%
CAS No.: 3006-96-0
Molecular Formula: C14H20O6
Molecular Weight: 284.31
Compound ID: 76360
Description: A base labile 4-hydroxymethylbenzoic acid (HMBA) linker,it was effectively removed at pH=10. The HMBA linker was demonstrated to be stable to the conditions required for native chemical ligation, subsequent transformations and final purification. The benzyl ester, which forms the HMBA linker with the first amino acid, is stable to piperidine, used for Fmoc group removal, making the linkage applicable for chemical elongation of a peptide sequence with Fmoc strategies.