PLHSpT

Description

Product name: PLHSpT

Catalog#: 1809065

Synonyms:

CAS NO.:

Sequence: Ac-Pro-Leu-His-Ser-pThr

M.W: C26H42N7O12P

M.F.: 675.63

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Polo-like kinase-1 (Plk1) plays a crucial role in cell proliferation and the inhibition of Plk1 has been considered as a potential target for specific inhibitory drugs in anti-cancer therapy.  Because of its essential role in cell proliferation, there has been a high level of interest to identify the interaction between Plk1 and its centromere/kinetochore-associated binding target, that led to the discovery of polo-box-interacting protein 1 (PBIP1) and a minimal peptide, PLHSpT (residues 74–78 of PBIP1) and its derivatives that exhibit high anti-Plk1-PBD activity.

Compound ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.