β-Amyloid (1–42, R5G)

Description

Product name: β-Amyloid (1–42, R5G)

Catalog#: 1244013

Organism:

Synonyms: D A E F G H D S G Y E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V I A

CAS NO.:107761-42-2

Sequence: Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

M.W: 4414.97

M.F.:

Purity: 95%

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Beta-amyloid protein is thought to play a major role in the development of Alzheimer’s disease. The more common form of the peptide has only 40 amino acids, but the 42AA peptide has a greater tendency to form plaques.High levels of plasma Aβ42 in patients with acute intracerebral hemorrhage are associated with a poor functional prognosis. Amyloid fibrils have been shown to exert their toxicity by modulating the immune system. Amyloid fibrils formed from different pathological or non-pathological proteins or peptides activate macrophages and microglia, leading to the secretion of pro-inflammatory molecules, such as TNF-α, IL-6, IL-1β and NO.

Uniprot ID:

Compound ID:

 

Usage: For Scientific Research Use Only, Not for Human Use.