1H-Benzotriazole

$150.00

Quantity: 500Gram

2 in stock

SKU: 8410023 Category:

Description

Product name: 1H-Benzotriazole

Synonym: BTA, Benzotriazole, 1,2,3-Benzotriazole, 2H-Benzotriazole, Azimidobenzene,

Catalog #: 8410023

Purity: 98%

CAS No.: 95-14-7

Molecular Formula: C6H5N3

Molecular Weight: 119.12

Description: Taurine-containing water-soluble peptidomimetics were designed and synthesized. N-terminal taurine acylations allowed synthesis of a number of taurine-containing peptides. N-protection of taurine with Cbz and SO2-activation with benzotriazole followed by coupling with various amino esters, dipeptides and nucleophiles provided taurine N- and O-conjugates and sulfonopeptides. Chiral peptides and iso-peptides were synthesized in excellent yield by using benzotriazole mediated solution phase synthesis. Benzotriazole acted both as activating and leaving group, eliminating frequent use of protection and subsequent deprotection. The procedure was based on the hypothesis that epimerization should be suppressed in solution due to a faster coupling rate than SPPS.

Compound ID: 7220

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