Quantity: 1 MG
Available on backorder
Product name: Eotaxin, human
Source: chemical synthesis
Synonyms: Eosinophil chemotactic protein,Small-inducible cytokine A11,
Purity: 95% by HPLC
Format: Lyophilized powder
Description: Eotaxins are important immune modulators that belong to the CC chemokine family.Eotaxin-1 (CCL-11) is a potent eosinophil chemoattractant that is considered a major contributor to tissue eosinophilia. Elevated eotaxin-1 levels have been described in various pathologic conditions, ranging from airway inflammation, to Hodgkin lymphoma, obesity and coronary artery disease. The main receptor for eotaxin-1 is CCR3; however, recent evidence indicates that eotaxin-1 may also bind to other receptors expressed by various cell types, suggesting a more widespread regulatory role for eotaxin-1 beyond the recruitment of eosinophils.
Uniprot ID: P51671
Usage: For Scientific Research Use Only, Not for Human Use.
Clinical Immunology, Volume 153, Issue 1, July 2014, Pages 199-208
Pulmonary Pharmacology & Therapeutics, Volume 27, Issue 2, April 2014, Pages 164-169.