Product name: Fmoc-L-Orn(N3)-OH
Synonym: Fmoc-L-δ-azidoornithine,Fmoc-5-azido-L-norvaline,(S)-5-Azido-2-(Fmoc-amino)pentanoic acid,(2S)-5-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid,
Catalog #: 8302046
CAS No.: 1097192-04-5
Molecular Formula: C20H20N4O4
Molecular Weight: 380.4
Compound ID: 25146062
Description: Deuterium substitution adjacent to the azide group in HomoAZAL and 5-azido-L-norvaline (N3-Norval) resulted in a large decrease in mutagenic potency when compared to the non-deuterium labeled compounds. Given that the reaction uses alkyne and azide functional groups that do not occur naturally, the application of CuAAC click chemistry in the rational design of drug delivery systems is well suited for coupling biomolecules such as peptides, proteins, and nucleic acids to the synthetic carrier. Cu(I)-catalyzed 1,3-dipolar cycloaddition of side chains modified with azido and alkynyl functions generate 1,4-disubstituted [1,2,3]triazolyl-containing compounds.