Product name: Fmoc-Lys(Me)3-OH·Cl
Synonym: Fmoc-Lys(Me)3-OH chloride ,[(5S)-5-carboxy-5-(9H-fluoren-9-ylmethoxycarbonylamino)pentyl]-trimethylazanium chloride,
Catalog #: 8219002
CAS No.: 201004-29-7
Molecular Formula: C24H31ClN2O4
Molecular Weight: 446.97
Compound ID: 51051589
Description: Deregulation of lysine methylation signalling has emerged as a common aetiological factor in cancer pathogenesis, with inhibitors of several histone lysine methyltransferases (KMTs) being developed as chemotherapeutics. Lysine methylation, like phosphorylation and acetylation, is a common PTM that regulates proteins in diverse cellular processes. KMTs catalyze mono-, di-, or tri-methylation by transfering one, two, or three methyl groups, respectively, from S-adenosyl-L-methionine to the ε-amino group of a lysine residue.